I know this is a late reply, but it will depend where you are located. Are you right on the coast, or are you further in-land? Where in VA are you located? (I'm down in the very southwest corner, and we have launched from multiple locations in and around Bristol.)
The main thing to take into account is where you are going to land. Run your flight predictions right up until the morning of launch, and if necessary, adjust your launch site accordingly. Once you let the balloon go you will have no control over it, and the best you can do is to set your launch site so that your landing site is somewhat accessible. We've scrubbed launches due to predicted landing sites being inaccessible at the time due to weather conditions.
I hope this helps, and if you have any other questions, please don't hesitate.